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DIM
Abnormally high estrogen levels in both men and women usually lead to cancer or other illnesses often associated with aging, including prostate disease, breast and uterine cancers, and weight gain. Supplementing the diet with DIM increases the metabolism for estrogen, multiplying the chance for estrogen to be broken down into its beneficial, or “good” estrogen metabolites. These “good” estrogen metabolites are known as the 2-hydroxy estrogens. Many of the benefits that are attributed to estrogen, which include its ability to protect the heart and brain with its antioxidant activity, are now known to come from these “good” metabolites. When DIM increases the “good” estrogen metabolites, there is a simultaneous reduction in the levels of undesirable or “bad” estrogen metabolites. These include the 16-hydroxy estrogens, which are not antioxidants and can actually cause cancer. Greater production of these “bad” estrogen metabolites is promoted by obesity and exposure to a number of manmade environmental chemicals. These “bad” estrogen metabolites are responsible for many of estrogen’s undesirable actions in women and men, including further unwanted weight gain, breast cancer, uterine cancer, and prostate cancer.