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Online Wellness Community Natural Health and Anti-Aging News
Online Wellness Community Natural Health and Anti-Aging News
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Epicatechin-flavonoid

Catechins include a variety of very potent anti-oxidant flavonoid molecules found in cocao, green tea and other known potent anti-oxidant food sources.

Variations are known as ECGC (most potent and expensive), EGC and ECG. These beneficial catechins are present in many plants. High quantities can be found in cocoa, tea and grapes and is why they are considered super anti-oxidants and provide health effects by protecting our cells from oxidative damage from free radicals. A number of chronic disease have been associated with free radical damage, including cancer, arteriosclerosis, heart diseases and accelerated aging. Epigallocatechin gallate interferes with many enzyme systems: it inhibits fast-binding and reversible fatty acid synthase, increases tyrosine phosphorylation of the insulin receptor, activation of ornithine decarboxylase. EGCG can protect the DNA in the human cells from ultraviolet and visible radiation-induced damage and may be effective in promoting fat oxidation and lowering body weight (increasingly of great consumer interest and a primary reason for increased green tea and green tea extract supplement usage).

The entire catechin family are very strong antioxidants. They have insulin mimic actions, seem to improve heart health and many many other benefits.

Dr. Norman Hollenberg of Harvard Medical School found that Kuna indians, who live on the San Blas Island Chain in Panama and drink high quantities of cocoa drinks, have a lower risk of stroke, heart failure, cancer and diabetes compared to the Indians living on the mainland. The high levels of this anti-oxidant in their diet seems to be the only distinguishing factor. Dr. Norman Hollenberg suggests epicatechin and other catechins be classified as a vitamin.

Diabetes Benefit – Studies show that epicatechin and other flavonoids exert a protective role on osmotic fragility of cells, similar to that of insulin. The mechanism of action of epicatechin is different to that of insulin and remains speculative. In diabetic red blood cells epicatechin causes an increase in acetylcholinesterase activity. This activity is significantly lower in type 2 diabetic patients.

Heart Benefits
– Epicatechin reduces lipid peroxidation and inhibits platelet aggregation. Epicatechin cause blood vessel dilation by regulating nitric oxide, a molecule secreted by the blood vessel endothelium to signal surrounding muscle to relax.

Cancer Benefits – EGCG is one of the nutrient extracts we expect to increasingly be used by cancer patients once intense nutritional therapy is part of cancer care.

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