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Online Wellness Community Natural Health and Anti-Aging News


GLUTATHIONE is the major antioxidant produced by the liver, protecting cells in your  body from free radicals. It has been referred to as the master antioxidant. Technically it is a tripeptide compound, not an amino acid, although the body produces it from the amino acids cysteine, glutamic acid and glycine.


  • increases the molecular effectiveness of other anti-oxidants
  • is both water and fat soluble
  • is a major anti-aging power molecule
  • Glutathione is a very important detoxifying agent, enabling the body to get rid of undesirable toxins and pollutants.It forms a soluble compound with the toxin that can then be excreted through the urine or the gut. Many cancer-producing chemicals, heavy metals, drug metabolites, etc. are disposed of in this way.
  • Glutathione plays a crucial role in maintaining a normal balance between oxidation and anti-oxidation. This, in turn, regulates many of the cell’s vital functions, such as the synthesis and repair of DNA, the synthesis of proteins and the activation and regulation of enzymes
  • Glutathione is required in many of the intricate steps needed to carry out an immune response
  • It also is needed for carbohydrate metabolism and the breakdown of oxidized fats.

The importance of glutathione cannot be overstated. Glutathione deficiencies are correlated with all manner of problems since a deficiency affects the nervous system first.

Glutathione values decline with age. Higher values in older people are seen to correlate with better health, underscoring the importance of this remarkable substance for maintaining a healthy, well-functioning body.

It is believed Glutathione does not survive or cannot be absorbed meaningfully in the GI tract. Nevertheless it appears increasingly in advanced medical grade supplements. It is bio-available sublingually or vaporized.

While the body benefits by high levels of glutathione, it is believed the body’s capacity to produce glutathione is limited to perhaps 300mg a day. Nutritional IV administration along with B12, selenium and other synergistic nutritive compounds  is an increasingly used complimentary therapy believed to have substantial and immediate benefits for a wide variety of ailments. Expanding such nutritional IV “cocktails” to include NAC and glycyrrhizic acid and other items may greatly increase potency and benefits.

Free radicals are highly reactive substances that, if left unchecked, will damage or destroy key cell components (e.g. membranes, DNA) in micro-seconds. Glutathione protects your cells from these free radicals. In addition, glutathione recycles other well-known anti-oxidants such as vitamin C and vitamin E, keeping them in their active state longer.

More from the American Academy of Antiaging Medicine (A4M):


Glutathione is a tripeptide composed of the three amino acids &emdash; glycine, glutamic acid (glutamate), and cysteine. Dietary glutathione can be found in fruit and vegetables, especially asparagus, avocado, and walnuts, fish, and meat.


Glutathione has been called the “master antioxidant,” in addition to its own potent antioxidant powers glutathione helps to recycle other antioxidants such as vitamins C and E. Thus, glutathione can help to protect against cancer andother diseases caused by oxidative damage. Glutathione also plays an important role in the regulation of immune cells, and is a potent detoxifying agent. Low levels of glutathione have been associated with hepatic dysfunction, immune dysfunction, cardiac disease, and premature aging. It is also important in DNA synthesis and repair, protein and prostaglandin synthesis, and amino acid transport. Several studies have shown that glutathione has antiviral properties. Research has shown that glutathione inhibits activation of the HIV virus, therefore it may be beneficial to people with HIV and AIDS.


There are no known symptoms of glutathione deficiency, however some medical conditions are associated with glutathione deficiency, for example diabetes, low sperm count, liver disease and autism/add/adhd. Heavy smokers may have low levels as certain chemicals in tobacco smoke increase the rate at which the body utilizes glutathione.

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