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Online Wellness Community Natural Health and Anti-Aging News
Online Wellness Community Natural Health and Anti-Aging News


PREGNENOLONE (Brain/AntiAging/Mood/Energy/DeTox/Inflammation/Nervous System)

The body makes pregnenolone out of cholesterol, however our body’s production of pregnenolone declines with age. Taking pregnenolone has been found to improve memory, reduce stress and enhance DHEA levels.

Also important, pregnenolone has been found to strengthen the myelin sheath membranes that are vital to the healthy functioning of our brains and nervous systems. Pregnenolone is the basic precursor for the production of ALL the human steroid hormones.

PREGNENOLONE IMPROVES MEMORY IN ANIMAL STUDIES: Several animal experiments reveal important clues to Pregnenolone’s beneficial effect on memory and learning ability.

Pregnenolone seems to reduce the excess release of, or reduce the negative effects of the adrenal stress steroid hormone Cortisol. Cortisol is toxic at high levels. Both acute and chronic stress release of excess Cortisol can damage the hippocampus, a mid-brain region essential to memory formation and retrieval. The mice experiment strongly suggests that Pregnenolone is able to blunt the normal memory damaging effects of excess stress related Cortisol.


Pregnenolone improves mood, and has a mild anti-depressant effect and also improves energy levels by protecting our energy producing mitochondria from toxins, which would otherwise damage the mitochondria.

Pregnenolone also enhances the activity of detoxifying enzymes, which help our cells (especially the liver and brain) to detoxify various poisons, whether environmental, or our own metabllically produced toxins. The body’s own production of Pregnenolone is reduced with aging, stress, depression, hypothyroidism and toxin exposure.

Pregnenolone may be a general “anti-stress” metabolite, which, however, may not always be present in our bodies at optimal levels, precisely because it may be used up in producing all the steroid hormones, not leaving enough to fulfill its stress buffer role.

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